Nampt activator-1( —— )

Catalog No. M36082 CAS No. 701929-65-9

NAMPT Activator-1 (compound 1) is an effective and specific activator of niacinamide phosphotransferase (Compound 1) with a wide range of EC50 (3.3-3.7 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Nampt activator-1
Note

Research use only, not for human use.
Brief Description

NAMPT Activator-1 (compound 1) is an effective and specific activator of niacinamide phosphotransferase (Compound 1) with a wide range of EC50 (3.3-3.7 μM).
Description

Nampt activator-1 (compound 1) is a potent Nicotinamide phosphoribosyltransferase (NAMPT) activator, with EC50 of 3.3-3.7 μM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

NAMPT
Recptor

NAMPT
Research Area

——
Indication

——

Chemical Information

CAS Number

701929-65-9
Formula Weight

299.32
Molecular Formula

C16H17N3O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (835.23 mM; Ultrasonic )
SMILES

CCOC(=O)c1ccc(NC(=O)NCc2ccncc2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Akiu M, et al. Discovery of 1-[2-(1-methyl-1H-pyrazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-3-(pyridin-4-ylmethyl)urea as a potent NAMPT (nicotinamide phosphoribosyltransferase) activator with attenuated CYP inhibition.[J]. Bioorganic & medicinal chemistry letters, 2021, 43:128048.

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