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LB-60-OF61
CAS No. 794461-93-1
LB-60-OF61( —— )
Catalog No. M32993 CAS No. 794461-93-1
LB-60-OF61 is a NAMPT inhibitor that exhibits antiproliferative activity against MYC oncogene-dependent cancer cell lines (brackets).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 251 | Get Quote |
|
| 5MG | 392 | Get Quote |
|
| 10MG | 645 | Get Quote |
|
| 25MG | 1214 | Get Quote |
|
| 50MG | 2052 | Get Quote |
|
| 100MG | 3132 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLB-60-OF61
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NoteResearch use only, not for human use.
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Brief DescriptionLB-60-OF61 is a NAMPT inhibitor that exhibits antiproliferative activity against MYC oncogene-dependent cancer cell lines (brackets).
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DescriptionLB-60-OF61 is a NAMPT inhibitor and is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines.
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In VitroLB-60-OF61 is potent against HCT116 cells with an IC50 around 30?nM as measured in a 384 well format.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetNAMPT
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RecptorNAMPT
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Research Area——
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Indication——
Chemical Information
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CAS Number794461-93-1
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Formula Weight494.59
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Molecular FormulaC29H30N6O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 200 mg/mL (404.38 mM; Ultrasonic )
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SMILESO=C(NCc1cccnc1)c1ccc(OCc2cc3cnc(nc3n2CCC2CCCCC2)C#N)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Estoppey D, et al. Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Sci Rep. 2017 Feb 16;7:42728.?
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