SBI-797812

CAS No. 2237268-08-3

SBI-797812( —— )

Catalog No. M22070 CAS No. 2237268-08-3

SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 97 In Stock
5MG 111 In Stock
10MG 201 In Stock
25MG 352 In Stock
50MG 551 In Stock
100MG 745 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SBI-797812
  • Note
    Research use only, not for human use.
  • Brief Description
    SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).
  • Description
    SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male C57BL/6?J mice (8-week-old)Dosage:20 mg/kg Administration:Intraperitoneal injection; administrated 1 h after fasting; added Buthanasia-D (165?mg/kg; i.p.) 4 h after fasting Result:Showed 0.311, 0.144, 0.078, and 0.078?μg/mg dry powder about NAD+ in liver, heart, gastrocnemius and quadriceps, respectively by LC-MS/MS measurement.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    NAMPT
  • Recptor
    NAMPT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2237268-08-3
  • Formula Weight
    402.47
  • Molecular Formula
    C19H22N4O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:250 mg/mL (621.16 mM; Need ultrasonic)
  • SMILES
    O=C(NCC1=CC=NC=C1)NC1=CC=C(C=C1)S(=O)(=O)N1CC2CCC(C1)O2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gardell SJ , et al. Boosting NAD+ with a small molecule that activates NAMPT. Nat Commun. 2019 Jul 19;10(1):3241.
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