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SBI-797812
CAS No. 2237268-08-3
SBI-797812( —— )
Catalog No. M22070 CAS No. 2237268-08-3
SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 111 | Get Quote |
|
| 10MG | 201 | Get Quote |
|
| 25MG | 426 | Get Quote |
|
| 50MG | 624 | Get Quote |
|
| 100MG | 889 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSBI-797812
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NoteResearch use only, not for human use.
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Brief DescriptionSBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).
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DescriptionSBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).
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In Vitro——
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In VivoAnimal Model:Male C57BL/6?J mice (8-week-old)Dosage:20 mg/kg Administration:Intraperitoneal injection; administrated 1 h after fasting; added Buthanasia-D (165?mg/kg; i.p.) 4 h after fasting Result:Showed 0.311, 0.144, 0.078, and 0.078?μg/mg dry powder about NAD+ in liver, heart, gastrocnemius and quadriceps, respectively by LC-MS/MS measurement.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetNAMPT
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RecptorNAMPT
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Research Area——
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Indication——
Chemical Information
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CAS Number2237268-08-3
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Formula Weight402.47
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Molecular FormulaC19H22N4O4S
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL (621.16 mM; Need ultrasonic)
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SMILESO=C(NCC1=CC=NC=C1)NC1=CC=C(C=C1)S(=O)(=O)N1CC2CCC(C1)O2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gardell SJ , et al. Boosting NAD+ with a small molecule that activates NAMPT. Nat Commun. 2019 Jul 19;10(1):3241.
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