Dihydrocurcumin

CAS No. 76474-56-1

Dihydrocurcumin( —— )

Catalog No. M35174 CAS No. 76474-56-1

Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dihydrocurcumin
  • Note
    Research use only, not for human use.
  • Brief Description
    Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response.
  • Description
    Dihydrocurcumin, a major metabolites of curcumin, reduces lipid accumulation and oxidative stress. Dihydrocurcumin regulates mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, increases protein expression levels of pAKT and PI3K, and reduced the levels of cellular NO and ROS via Nrf2 signaling pathways.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    PPAR
  • Recptor
    PPAR | Fatty Acid Synthase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    76474-56-1
  • Formula Weight
    370.4
  • Molecular Formula
    C21H22O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (67.49 mM; Ultrasonic (<60°C)
  • SMILES
    COc1cc(CCC(=O)\C=C(/O)\C=C\c2ccc(O)c(OC)c2)ccc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yu Q, et al. Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells. Biomed Pharmacother. 2018 Jul;103:1327-1336.?
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