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Aldi-6
CAS No. 2138-34-3
Aldi-6( Aldi6 )
Catalog No. M13408 CAS No. 2138-34-3
A novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameAldi-6
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NoteResearch use only, not for human use.
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Brief DescriptionA novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.
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DescriptionA novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively; decreases SCC4 cells viability, sensitizes HNSCC cells to cisplatin; the combination of Aldi-6 and cisplatin causes a greater reduction in tumor burden in vivo than cisplatin alone.
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In Vitro——
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In Vivo——
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SynonymsAldi6
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PathwayMetabolic Enzyme/Protease
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TargetALDH
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RecptorALDH
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Research Area——
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Indication——
Chemical Information
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CAS Number2138-34-3
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Formula Weight256.143
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Molecular FormulaC11H14BrNO
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Purity>98% (HPLC)
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Solubility——
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SMILESCN(C)CCC(=O)C1=CC=C(C=C1)Br
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Chemical Name1-(4-bromophenyl)-3-(dimethylamino)propan-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kim J, et al. Oncotarget. 2017 Apr 10. doi: 10.18632/oncotarget.17017.
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