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Scutellarein

CAS No. 529-53-3

Scutellarein( Scutellarein | 4',5,6,7-Tetrahydroxyflavone )

Catalog No. M17533 CAS No. 529-53-3

Scutellarein reduces inflammatory responses by inhibiting Src kinase activity.

Purity : >98% (HPLC)

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Biological Information

Product Name

Scutellarein
Note

Research use only, not for human use.
Brief Description

Scutellarein reduces inflammatory responses by inhibiting Src kinase activity.
Description

Scutellarein is natural product. Scutellarein from Scutellaria barbata induces apoptosis of human colon cancer HCT116 cells through the ROS-mediated mitochondria-dependent pathway. Scutellarein Reduces Inflammatory Responses by Inhibiting Src Kinase Activity.
In Vitro

——
In Vivo

Animal Model:HFD mice Dosage:50 mg/kg Administration:in diet, 16 weeks Result:Reduced lipid accumulation and levels of inflammatory factors in the liver.
Synonyms

Scutellarein | 4',5,6,7-Tetrahydroxyflavone
Pathway

Cell Cycle/DNA Damage
Target

GPR
Recptor

Src
Research Area

Others-Field
Indication

——

Chemical Information

CAS Number

529-53-3
Formula Weight

286.24
Molecular Formula

C15H10O6
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 30 mg/mL; 104.81 mM
SMILES

c1cc(ccc1c1cc(=O)c2c(c(c(cc2o1)O)O)O)O
Chemical Name

5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Sung NY, et al. Korean J Physiol Pharmacol. 2015 Sep;19(5):441-9.

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