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XPW1

CAS No. 2700286-66-2

XPW1( —— )

Catalog No. M37124 CAS No. 2700286-66-2

XPW1 is a new potent and selective CDK9 inhibitor with antitumour activity that transcriptionally inhibits the DNA repair process in ccRCC cells.XPW1 can be used to study clear cell renal cell carcinoma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 170 In Stock
10MG 275 In Stock
25MG 550 In Stock
50MG 886 In Stock
100MG 1386 In Stock
200MG 1823 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    XPW1
  • Note
    Research use only, not for human use.
  • Brief Description
    XPW1 is a new potent and selective CDK9 inhibitor with antitumour activity that transcriptionally inhibits the DNA repair process in ccRCC cells.XPW1 can be used to study clear cell renal cell carcinoma.
  • Description
    XPW1 is a potent and selective CDK9 inhibitor with excellent activity against clear cell renal cell carcinoma (ccRCC) and low toxicity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    CDK
  • Recptor
    CDK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2700286-66-2
  • Formula Weight
    656.19
  • Molecular Formula
    C36H39ClFN7O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 31.25 mg/mL (47.62 mM; Ultrasonic (<60°C)
  • SMILES
    ClC1=C(C=2N=C(NCC3=CC(F)=CC=C3)C=CC2)C=C(N[C@H]4CC[C@H](NC(=O)C5=CC=C(NC(/C=C/CN(C)C)=O)C=C5)CC4)N=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kuang Z, et al. The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma. Br J Cancer. 2023 Oct 26.?
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