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CDK12-IN-3
CAS No. 2220184-50-7
CDK12-IN-3( —— )
Catalog No. M33320 CAS No. 2220184-50-7
CDK12-IN-3 is a selective and potent CDK12 inhibitor with anti-tumor activity, which can be used to study malignant tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 345 | In Stock |
|
| 5MG | 312 | In Stock |
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| 10MG | 511 | In Stock |
|
| 25MG | 1074 | In Stock |
|
| 50MG | 1758 | In Stock |
|
| 100MG | 2325 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCDK12-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionCDK12-IN-3 is a selective and potent CDK12 inhibitor with anti-tumor activity, which can be used to study malignant tumors.
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DescriptionCDK12-IN-3 is a potent and selective CDK12 inhibitor with an IC50 of 491 nM in enzymatic assay.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetCDK
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RecptorCDK
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Research Area——
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Indication——
Chemical Information
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CAS Number2220184-50-7
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Formula Weight470.52
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Molecular FormulaC23H28F2N8O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (531.33 mM; Ultrasonic )
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SMILESCC(C)n1cnc2c(NCc3nc4ccc(F)c(F)c4[nH]3)nc(nc12)N1CCCC[C@H]1CCO
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Johannes JW, et al. Structure-Based Design of Selective Noncovalent CDK12 Inhibitors. ChemMedChem. 2018 Feb 6;13(3):231-235.?
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