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Xanthine oxidoreductase-IN-5
CAS No. 1026652-90-3
Xanthine oxidoreductase-IN-5( —— )
Catalog No. M36446 CAS No. 1026652-90-3
Xanthine oxidoreductase-IN-5 is an orally active inhibitor of xanthine oxidoreductase (XOR) with an IC50 of 55 nM. Xanthine oxidoreductase-IN-5 may be used in studies of acute hyperuricemia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 129 | Get Quote |
|
| 5MG | 190 | Get Quote |
|
| 10MG | 314 | Get Quote |
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| 25MG | 512 | Get Quote |
|
| 50MG | 720 | Get Quote |
|
| 100MG | 981 | Get Quote |
|
| 500MG | 2007 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameXanthine oxidoreductase-IN-5
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NoteResearch use only, not for human use.
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Brief DescriptionXanthine oxidoreductase-IN-5 is an orally active inhibitor of xanthine oxidoreductase (XOR) with an IC50 of 55 nM. Xanthine oxidoreductase-IN-5 may be used in studies of acute hyperuricemia.
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DescriptionXanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 55 nM. Xanthine oxidoreductase-IN-5 can be used for the research of acute hyperuricemia.
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In Vitro——
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In VivoAnimal Model:ICR mice (18-22 g) were induced acute hyperuricemia by injection of potassium oxonate and hypoxanthine Dosage:5 mg/kg Administration:Suspended in 0.5% CMC-Na solution for intragastric administration Result:Showed a uric acid-lowering effect from 5 h after administration.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetXanthine Oxidase (XAO)
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RecptorXanthine Oxidase
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Research Area——
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Indication——
Chemical Information
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CAS Number1026652-90-3
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Formula Weight323.35
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Molecular FormulaC17H17N5O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC(NC1=CC=C(OC(C)C)C=C1)(=O)C2=CC=C(C=C2)C=3NN=NN3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Peng W, et, al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947.?
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