Cart
sales@molnova.com
Home - Products - Metabolic Enzyme/Protease - Xanthine Oxidase (XAO) - Xanthine oxidoreductase-IN-3

Xanthine oxidoreductase-IN-3

CAS No. 651769-78-7

Xanthine oxidoreductase-IN-3( —— )

Catalog No. M36445 CAS No. 651769-78-7

Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 of 26.3 nM, suitable for use in acute hyperuricemia studies.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 392 Get Quote
5MG 610 Get Quote
10MG 867 Get Quote
25MG 1260 Get Quote
50MG 1702 Get Quote
100MG 2250 Get Quote
500MG 4410 Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Xanthine oxidoreductase-IN-3
  • Note
    Research use only, not for human use.
  • Brief Description
    Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 of 26.3 nM, suitable for use in acute hyperuricemia studies.
  • Description
    Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia.
  • In Vitro
    ——
  • In Vivo
    Animal Model:ICR mice (18-22 g) were induced acute hyperuricemia by injection of potassium oxonate and hypoxanthineDosage:5 mg/kg Administration:Suspended in 0.5% CMC-Na solution for intragastric administration Result:Showed a uric acid-lowering effect from 3 h after administration.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Xanthine Oxidase (XAO)
  • Recptor
    Xanthine Oxidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    651769-78-7
  • Formula Weight
    299.72
  • Molecular Formula
    C14H10ClN5O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(NC1=CC=C(Cl)C=C1)(=O)C2=CC=C(C=C2)C=3NN=NN3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Peng W, et, al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Purpurogallin

    Purpurogallin is a naturally phenol extracted from the plants of Quercus spp.

  • Tigulixostat

    Tigulixostat (LC350189) is a novel xanthine oxidase inhibitor (XOI) that reduces uric acid production and may be used in studies of gout-related diseases.

  • Xanthine oxidase-IN-...

    Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM.

Sign In Join Free