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Xanthine oxidoreductase-IN-3
CAS No. 651769-78-7
Xanthine oxidoreductase-IN-3( —— )
Catalog No. M36445 CAS No. 651769-78-7
Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 of 26.3 nM, suitable for use in acute hyperuricemia studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 257 | In Stock |
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| 10MG | 364 | In Stock |
|
| 25MG | 546 | In Stock |
|
| 50MG | 728 | In Stock |
|
| 100MG | 995 | In Stock |
|
| 200MG | 1349 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameXanthine oxidoreductase-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionXanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 of 26.3 nM, suitable for use in acute hyperuricemia studies.
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DescriptionXanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia.
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In Vitro——
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In VivoAnimal Model:ICR mice (18-22 g) were induced acute hyperuricemia by injection of potassium oxonate and hypoxanthineDosage:5 mg/kg Administration:Suspended in 0.5% CMC-Na solution for intragastric administration Result:Showed a uric acid-lowering effect from 3 h after administration.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetXanthine Oxidase (XAO)
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RecptorXanthine Oxidase
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Research Area——
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Indication——
Chemical Information
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CAS Number651769-78-7
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Formula Weight299.72
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Molecular FormulaC14H10ClN5O
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Purity>98% (HPLC)
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Solubility——
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SMILESC(NC1=CC=C(Cl)C=C1)(=O)C2=CC=C(C=C2)C=3NN=NN3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Peng W, et, al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947.?
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