GSK-3β inhibitor 14( —— )

Catalog No. M36031 CAS No. 863004-48-2

GSK-3β inhibitor 14 (1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-) is a weak GSK-3β inhibitor, IC50﹥ 100μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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5MG	114	In Stock
10MG	174	In Stock
25MG	296	In Stock
50MG	419	In Stock
100MG	577	In Stock
200MG	793	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

GSK-3β inhibitor 14
Note

Research use only, not for human use.
Brief Description

GSK-3β inhibitor 14 (1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-) is a weak GSK-3β inhibitor, IC50﹥ 100μM.
Description

GSK-3β inhibitor 14 (Compound 6i), benzothiazepinone derivative, is a weak GSK-3β inhibitor (IC50 >100 μM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

PI3K/Akt/mTOR signaling
Target

GSK-3
Recptor

GSK-3
Research Area

——
Indication

——

Chemical Information

CAS Number

863004-48-2
Formula Weight

283.39
Molecular Formula

C17H17NOS
Purity

>98% (HPLC)
Solubility

——
SMILES

C(N1C=2C(SC(C)CC1=O)=CC=CC2)C3=CC=CC=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Zhang P, et al. Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Eur J Med Chem. 2013 Mar;61:95-103.?

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