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MMP2-IN-2
CAS No. 1772-39-0
MMP2-IN-2( —— )
Catalog No. M35438 CAS No. 1772-39-0
MMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC50 of 4.2 μM, and it also shows inhibitory activity against MMP-13, MMP-9, and MMP-8 with IC50 values of 12, 23.3, and 25 μM, respectively .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 52 | In Stock |
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| 5MG | 73 | In Stock |
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| 10MG | 117 | In Stock |
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| 25MG | 220 | In Stock |
|
| 50MG | 348 | In Stock |
|
| 100MG | 557 | In Stock |
|
| 500MG | 1152 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMMP2-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionMMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC50 of 4.2 μM, and it also shows inhibitory activity against MMP-13, MMP-9, and MMP-8 with IC50 values of 12, 23.3, and 25 μM, respectively .
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DescriptionMMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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RecptorMMP
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Research Area——
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Indication——
Chemical Information
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CAS Number1772-39-0
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Formula Weight284.23
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Molecular FormulaC13H8N4O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 7.14 mg/mL (25.12 mM; Ultrasonic (<60°C)
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SMILESO=[N+]([O-])C1=CC=C(C2=NC3=CC=C([N+]([O-])=O)C=C3N2)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257. ?
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