Corylin

CAS No. 53947-92-5

Corylin( —— )

Catalog No. M19328 CAS No. 53947-92-5

Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 52 In Stock
5MG 80 In Stock
10MG 113 In Stock
25MG 222 In Stock
50MG 315 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Corylin
  • Note
    Research use only, not for human use.
  • Brief Description
    Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.
  • Description
    Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.
  • In Vitro
    Western Blot Analysis Cell Line:HepG2 and Huh7 cells Concentration:3-30 μM Incubation Time:24-48 h Result:Reduced the expression of EMT-promoting proteins such as N-cadherin, vimentin, slug, and twist.
  • In Vivo
    Animal Model:HFD- and DIO-treated miceDosage:50-100 mg/kg Administration:Oral gavage (p.o.), daily, 9 weeks Result:Reduced the weight of subcutaneous, visceral WAT, and body.Decreased the size of WAT adipocyte. Increased insulin sensitivity, mitochondrial biogenesis, and β-oxidation.Reduced serum levels of insulin and leptin and improved HOMA-IR.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    Others
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    53947-92-5
  • Formula Weight
    320.3
  • Molecular Formula
    C20H16O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 100 mg/mL 312.17 mM; H2O : < 0.1 mg/mL
  • SMILES
    CC1(C=CC2=C(O1)C=CC(=C2)C3=COC4=C(C3=O)C=CC(=C4)O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lee SW, et al. Phenolic compounds isolated from Psoralea corylifolia inhibit IL-6-induced STAT3 activation. Planta Med. 2012 Jun;78(9):903-6.
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