Cis-22a( —— )

Catalog No. M35266 CAS No. 1819366-84-1

Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	299	In Stock
10MG	556	In Stock
25MG	890	In Stock
50MG	1181	In Stock
100MG	1600	In Stock
200MG	Get Quote	In Stock
500MG	3190	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Cis-22a
Note

Research use only, not for human use.
Brief Description

Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.
Description

TRPV6-IN-1 is a potent and selective TRPV6 inhibitor. TRPV6-IN-1 has anti-proliferative effect and can be used for the research of cancer.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Calcium Channel
Recptor

Calcium Channel | TRP/TRPV Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

1819366-84-1
Formula Weight

449.51
Molecular Formula

C24H30F3N3O2
Purity

>98% (HPLC)
Solubility

——
SMILES

C(C(O)=O)(F)(F)F.CC=1C=C([C@H]2CC[C@H](CC2)N3CCN(CC3)C=4C=CC=NC4)C=CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Simonin C, et al. Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand-Based Virtual Screening Method. Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14748-52.?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks