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Cis-22a
CAS No. 1819366-84-1
Cis-22a( —— )
Catalog No. M35266 CAS No. 1819366-84-1
Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 299 | In Stock |
|
| 10MG | 556 | In Stock |
|
| 25MG | 890 | In Stock |
|
| 50MG | 1181 | In Stock |
|
| 100MG | 1600 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 3190 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCis-22a
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NoteResearch use only, not for human use.
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Brief DescriptionCis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.
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DescriptionTRPV6-IN-1 is a potent and selective TRPV6 inhibitor. TRPV6-IN-1 has anti-proliferative effect and can be used for the research of cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel | TRP/TRPV Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number1819366-84-1
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Formula Weight449.51
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Molecular FormulaC24H30F3N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC(C(O)=O)(F)(F)F.CC=1C=C([C@H]2CC[C@H](CC2)N3CCN(CC3)C=4C=CC=NC4)C=CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Simonin C, et al. Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand-Based Virtual Screening Method. Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14748-52.?
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