Cart
sales@molnova.com
(E/Z)-SIB-1893
CAS No. 6266-99-5
(E/Z)-SIB-1893( —— )
Catalog No. M33927 CAS No. 6266-99-5
(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant activity .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 64 | Get Quote |
|
| 10MG | 112 | Get Quote |
|
| 25MG | 227 | Get Quote |
|
| 50MG | 361 | Get Quote |
|
| 100MG | 533 | Get Quote |
|
| 500MG | 1152 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product Name(E/Z)-SIB-1893
-
NoteResearch use only, not for human use.
-
Brief Description(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant activity .
-
Description(E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist.
-
In Vitro——
-
In Vivo(E)-SIB-1893 produces hypothermia in freely moving rats in a dose-dependent manner.
-
Synonyms——
-
PathwayNeuroscience
-
TargetGluR
-
RecptorGluR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number6266-99-5
-
Formula Weight195.26
-
Molecular FormulaC14H13N
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (512.14 mM; Ultrasonic )
-
SMILESC(=CC1=CC=CC=C1)C=2N=C(C)C=CC2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. ?uszczki JJ, et al. Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats. Pharmacol Rep. 2005;57(6):795-801.?
molnova catalog
related products
-
Motolimod
Motolimod (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.
-
L-Cysteinesulfinic a...
L-Cysteinesulfinic acid monohydrate is a potent agonist at rat metabotropic glutamate receptors (mGluRs).
-
Sibiricose A6
Sibiricose A6 displays antidepressant-like action, it may prevent or relieve depression.
