(E/Z)-SIB-1893

CAS No. 6266-99-5

(E/Z)-SIB-1893( —— )

Catalog No. M33927 CAS No. 6266-99-5

(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant activity .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 64 In Stock
10MG 112 In Stock
25MG 235 In Stock
50MG 365 In Stock
100MG 551 In Stock
200MG Get Quote In Stock
500MG 1190 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    (E/Z)-SIB-1893
  • Note
    Research use only, not for human use.
  • Brief Description
    (E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant activity .
  • Description
    (E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist.
  • In Vitro
    ——
  • In Vivo
    (E)-SIB-1893 produces hypothermia in freely moving rats in a dose-dependent manner.
  • Synonyms
    ——
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    GluR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6266-99-5
  • Formula Weight
    195.26
  • Molecular Formula
    C14H13N
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (512.14 mM; Ultrasonic )
  • SMILES
    C(=CC1=CC=CC=C1)C=2N=C(C)C=CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. ?uszczki JJ, et al. Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats. Pharmacol Rep. 2005;57(6):795-801.?
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