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HexylHIBO
CAS No. 334887-43-3
HexylHIBO( —— )
Catalog No. M33866 CAS No. 334887-43-3
HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 140 | In Stock |
|
| 10MG | 207 | In Stock |
|
| 25MG | 487 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameHexylHIBO
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NoteResearch use only, not for human use.
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Brief DescriptionHexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
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DescriptionHexylHIBO is a potent group I mGluR antagonist with Kbs of 140 and 110 μM at mGlu1a and mGlu5a receptors, respectively. HexylHIBO decreased sEPSC in rat.
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In VitroThus ambient levels of glutamate tonically activate mGluRs and regulate cortical excitability.
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In Vivo——
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Synonyms——
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PathwayNeuroscience
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TargetGluR
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RecptorGluR
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Research Area——
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Indication——
Chemical Information
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CAS Number334887-43-3
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Formula Weight256.3
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Molecular FormulaC12H20N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESC(CCCCC)C1=C(CC(C(O)=O)N)ONC1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Madsen U, et al. Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors. J Med Chem. 2001;44(7):1051-1059.?
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