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4-oxo-1,4-dihydroquinoline-2-carboxylic acid
CAS No. 13593-94-7
4-oxo-1,4-dihydroquinoline-2-carboxylic acid( 1,4-DIHYDRO-4-OXOQUINOLINE-2-CARBOXYLIC ACID )
Catalog No. M22261 CAS No. 13593-94-7
4-oxo-1,4-dihydroquinoline-2-carboxylic acid is a GluR and NMDA inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
|
| 50MG | 36 | In Stock |
|
| 100MG | 51 | In Stock |
|
| 200MG | 74 | In Stock |
|
| 500MG | 124 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name4-oxo-1,4-dihydroquinoline-2-carboxylic acid
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NoteResearch use only, not for human use.
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Brief Description4-oxo-1,4-dihydroquinoline-2-carboxylic acid is a GluR and NMDA inhibitor.
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Description4-oxo-1,4-dihydroquinoline-2-carboxylic acid is a GluR and NMDA inhibitor.
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In VitroTranstorine shows growth inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Enterobacter cloacae, with MIC 0.38, 0.5, and 0.45 mg/mL, respectively.
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In Vivo——
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Synonyms1,4-DIHYDRO-4-OXOQUINOLINE-2-CARBOXYLIC ACID
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PathwayNeuroscience
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TargetGluR
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RecptorGluR|NMDA receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number13593-94-7
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Formula Weight189.17
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Molecular FormulaC10H7NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 10 mg/mL (52.86 mM)
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SMILESOC(=O)c2cc(=O)c1ccccc1n2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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LY382884
LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.
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Basimglurant
Basimglurant is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM). In competition binding experiments on human recombinant mGlu5, Basimglurant (RG7090) fully displaces [3H]-MPEP with a Ki of 35.6 nM and [3H]-ABP688 with a Ki of 1.4 nM. In HEK293 cells stably expressing human mGlu5, Basimglurant (RG7090) inhibits quisqualate induced Ca2+ mobilization with an IC50 of 7.0 nM and [3H]-inositolphosphate accumulation (IC50 of 5.9 nM).
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TCN 238
TCN 238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).
