ABP688( —— )

Catalog No. M34150 CAS No. 924298-51-1

ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

ABP688
Note

Research use only, not for human use.
Brief Description

ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.
Description

ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Neuroscience
Target

GluR
Recptor

GluR
Research Area

——
Indication

——

Chemical Information

CAS Number

924298-51-1
Formula Weight

240.3
Molecular Formula

C15H16N2O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 83.33 mg/mL (346.77 mM; Ultrasonic )
SMILES

C(#CC=1N=C(C)C=CC1)C2=CC(=NOC)CCC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hintermann S, et al. ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies. Bioorg Med Chem. 2007 Jan 15;15(2):903-14. ?

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