DMeOB
CAS No. 40252-74-2
DMeOB( —— )
Catalog No. M33845 CAS No. 40252-74-2
DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and can be used to study neurological diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 73 | In Stock |
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| 25MG | 148 | In Stock |
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| 50MG | 230 | In Stock |
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| 100MG | 368 | In Stock |
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| 200MG | 538 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDMeOB
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NoteResearch use only, not for human use.
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Brief DescriptionDMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and can be used to study neurological diseases.
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DescriptionDMeOB is an agonist ofmGluR5 receptor with an IC50 of 3 μM. DMeOB has a negative modulatory effect.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayNeuroscience
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TargetGluR
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RecptorGluR
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Research Area——
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Indication——
Chemical Information
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CAS Number40252-74-2
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Formula Weight268.31
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Molecular FormulaC16H16N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESN(N=CC=1C=CC=C(OC)C1)=CC=2C=CC=C(OC)C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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S 18986
S 18986 is a selective, orally active, brain-penetrant positive allosteric modulator of AMPA-type receptors that enhances cognition in rodents by inducing the release of noradrenaline and acetylcholine in the rat hippocampus, subsequently improving object-recognition memory.
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ML289
ML289 (VU0463597) is a potent, selective, and CNS-penetrant negative allosteric modulator of mGlu3 (IC50=0.66 μM), with over 15-fold selectivity compared to mGlu2 and no activity against mGlu5.
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Memantine hydrochlor...
Memantine is an uncompetitive NMDA receptor antagonist. When using HEK293 cells express recombinant rat NMDA receptors, memantine shows inhibition of L-glutamate-mediated response with a dose- and voltage-dependent manner.
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