MAFP( —— )

Catalog No. M33424 CAS No. 188404-10-6

MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective, active-site directed irreversible inhibitor of anandamide amidase, cPLA2, and iPLA2.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

MAFP
Note

Research use only, not for human use.
Brief Description

MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective, active-site directed irreversible inhibitor of anandamide amidase, cPLA2, and iPLA2.
Description

MAFP (Methyl Arachidonyl Fluorophosphonate) is an selective, active-site directed and irreversible inhibitor of cPLA2 and iPLA2. MAFP is also a potent irreversible inhibitor of anandamide amidase.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Phospholipase
Recptor

Phospholipase
Research Area

——
Indication

——

Chemical Information

CAS Number

188404-10-6
Formula Weight

370.48
Molecular Formula

C21H36FO2P
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 100 mg/mL (269.92 mM; )Methyl Acetate : ≥ 10 mg/mL (26.99 mM)
SMILES

C(/C=C\C/C=C\C/C=C\C/C=C\CCCCC)CCCP(OC)(F)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lio YC, et al. Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate. Biochim Biophys Acta. 1996 Jul 12;1302(1):55-60.?

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