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S-(4-Hydroxybenzyl)glutathione
CAS No. 129636-38-0
S-(4-Hydroxybenzyl)glutathione( L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] | S-(4-Hydroxybenzyl)glutathione )
Catalog No. M29436 CAS No. 129636-38-0
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 170 | In Stock |
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| 5MG | 148 | In Stock |
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| 10MG | 217 | In Stock |
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| 25MG | 370 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameS-(4-Hydroxybenzyl)glutathione
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NoteResearch use only, not for human use.
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Brief DescriptionL-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
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DescriptionL-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.(In Vitro):L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] inhibits specific [3H]kainic acid binding to brain glutamate receptors with IC50 of 2 μM. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.
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In VitroS-(4-Hydroxybenzyl)glutathione inhibits the binding of specific [3H]kainic acid to brain glutamate receptors, with an IC50 of 2 μM.
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In Vivo——
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SynonymsL-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] | S-(4-Hydroxybenzyl)glutathione
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PathwayNeuroscience
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TargetGluR
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RecptorGluR
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Research Area——
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Indication——
Chemical Information
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CAS Number129636-38-0
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Formula Weight413.45
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Molecular FormulaC17H23N3O7S
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Purity>98% (HPLC)
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Solubility——
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SMILESN[C@@H](CCC(N[C@@H](CSCc(cc1)ccc1O)C(NCC(O)=O)=O)=O)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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DMeOB
DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and can be used to study neurological diseases.
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HBT1
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.HBT1 bound to the ligand-binding domain (LBD) of AMPA-R in a glutamate-dependent manner.?
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Basimglurant
Basimglurant is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM). In competition binding experiments on human recombinant mGlu5, Basimglurant (RG7090) fully displaces [3H]-MPEP with a Ki of 35.6 nM and [3H]-ABP688 with a Ki of 1.4 nM. In HEK293 cells stably expressing human mGlu5, Basimglurant (RG7090) inhibits quisqualate induced Ca2+ mobilization with an IC50 of 7.0 nM and [3H]-inositolphosphate accumulation (IC50 of 5.9 nM).
