S-(4-Hydroxybenzyl)glutathione
CAS No. 129636-38-0
S-(4-Hydroxybenzyl)glutathione( L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] | S-(4-Hydroxybenzyl)glutathione )
Catalog No. M29436 CAS No. 129636-38-0
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 170 | In Stock |
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| 5MG | 148 | In Stock |
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| 10MG | 217 | In Stock |
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| 25MG | 370 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameS-(4-Hydroxybenzyl)glutathione
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NoteResearch use only, not for human use.
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Brief DescriptionL-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
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DescriptionL-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.(In Vitro):L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] inhibits specific [3H]kainic acid binding to brain glutamate receptors with IC50 of 2 μM. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.
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In VitroS-(4-Hydroxybenzyl)glutathione inhibits the binding of specific [3H]kainic acid to brain glutamate receptors, with an IC50 of 2 μM.
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In Vivo——
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SynonymsL-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] | S-(4-Hydroxybenzyl)glutathione
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PathwayNeuroscience
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TargetGluR
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RecptorGluR
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Research Area——
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Indication——
Chemical Information
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CAS Number129636-38-0
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Formula Weight413.45
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Molecular FormulaC17H23N3O7S
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Purity>98% (HPLC)
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Solubility——
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SMILESN[C@@H](CCC(N[C@@H](CSCc(cc1)ccc1O)C(NCC(O)=O)=O)=O)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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JNJ-46778212
JNJ-46778212 (VU 0409551) is a potent and selective mGlu5 allosteric modulator (EC50: 260 nM) used for neurodissection studies.
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FPTQ B
FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively . In addition to its robust inhibitory properties, FPTQ exhibits notable antioxidant and anti-inflammatory effects in both in vitro and in vivo settings .
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ML 254
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinase (DMPK) properties for systemic dosing in rodents.
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