Cart
sales@molnova.com
YH-306
CAS No. 1373764-75-0
YH-306( YH306 )
Catalog No. M27784 CAS No. 1373764-75-0
YH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 10MG | 32 | In Stock |
|
| 25MG | 65 | In Stock |
|
| 50MG | 96 | In Stock |
|
| 100MG | 145 | In Stock |
|
| 200MG | 214 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameYH-306
-
NoteResearch use only, not for human use.
-
Brief DescriptionYH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
-
DescriptionYH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.(In Vitro):YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1, and the expression of MMP2 and MMP9. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 inhibits Arp2/3 complex-mediated actin polymerization.
-
In Vitro——
-
In Vivo——
-
SynonymsYH306
-
PathwayMetabolic Enzyme/Protease
-
TargetMMP
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1373764-75-0
-
Formula Weight306.365
-
Molecular FormulaC19H18N2O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 20 mg/mL (65.28 mM)
-
SMILESOc1ccc(CC(=O)N2CCc3c(C2)[nH]c2ccccc32)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
MMP13-IN-3
MMP13-IN-3 is >1000 selective over other MMPs. MMP13-IN-3 is an effective, selective, and orally active MMP-13 inhibitor (IC50=1 nM) for the potential treatment of osteoarthritis.
-
Marimastat
A broad spectrum MMP inhibitor for MMP9/1/2/14/7 with IC50 of 3/5/6/9/13 nM, respectively.
-
Histatin 5 (TFA)(115...
Histatin 5 TFA inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.Histatin 5 is a member of a family of low-molecular-weight salivary proteins secreted by parotid, submandibular, and sublingual glands. Using biotinylated gelatin as a substrate, Histatin 5 is found to inhibit the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
