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Decursinol angelate

CAS No. 130848-06-5

Decursinol angelate( —— )

Catalog No. M23465 CAS No. 130848-06-5

Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 105 In Stock
25MG 224 In Stock
50MG 336 In Stock
100MG 497 In Stock
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Biological Information

  • Product Name
    Decursinol angelate
  • Note
    Research use only, not for human use.
  • Brief Description
    Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway.
  • Description
    Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    ERK
  • Recptor
    ERK|JNK|PKC|VEGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    130848-06-5
  • Formula Weight
    328.36
  • Molecular Formula
    C19H20O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:65 mg/mL (197.95 mM)
  • SMILES
    C/C=C(C)\C(O[C@H]1CC(C=C(C=CC(O2)=O)C2=C3)=C3OC1(C)C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Decursin and decursinol angelate improve wound healing by upregulating transcription of genes encoding extracellular matrix remodeling proteins, inflammatory cytokines, and growth factors in human keratinocytes.Biochem Biophys Res Commun. 2018 May 23;499(4):979-984.
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