Decursinol angelate

Research use only, not for human use.

Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway.

Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.

——

——

——

MAPK/ERK Signaling

ERK

ERK|JNK|PKC|VEGFR

——

——

130848-06-5

328.36

C19H20O5

>98% (HPLC)

DMSO:65 mg/mL (197.95 mM)

C/C=C(C)\C(O[C@H]1CC(C=C(C=CC(O2)=O)C2=C3)=C3OC1(C)C)=O

——

(-20℃)

With Ice Pack

≥ 2 years