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Decursinol angelate
CAS No. 130848-06-5
Decursinol angelate( —— )
Catalog No. M23465 CAS No. 130848-06-5
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 52 | In Stock |
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| 5MG | 41 | In Stock |
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| 10MG | 65 | In Stock |
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| 25MG | 142 | In Stock |
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| 50MG | 207 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDecursinol angelate
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NoteResearch use only, not for human use.
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Brief DescriptionDecursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway.
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DescriptionDecursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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TargetERK
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RecptorERK|JNK|PKC|VEGFR
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Research Area——
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Indication——
Chemical Information
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CAS Number130848-06-5
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Formula Weight328.36
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Molecular FormulaC19H20O5
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Purity>98% (HPLC)
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SolubilityDMSO:65 mg/mL (197.95 mM)
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SMILESC/C=C(C)\C(O[C@H]1CC(C=C(C=CC(O2)=O)C2=C3)=C3OC1(C)C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Decursin and decursinol angelate improve wound healing by upregulating transcription of genes encoding extracellular matrix remodeling proteins, inflammatory cytokines, and growth factors in human keratinocytes.Biochem Biophys Res Commun. 2018 May 23;499(4):979-984.
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