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CP 424174
CAS No. 210825-31-3
CP 424174( —— )
Catalog No. M22980 CAS No. 210825-31-3
CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 64 | In Stock |
|
| 5MG | 90 | In Stock |
|
| 10MG | 137 | In Stock |
|
| 25MG | 246 | In Stock |
|
| 50MG | 368 | In Stock |
|
| 100MG | 536 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCP 424174
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NoteResearch use only, not for human use.
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Brief DescriptionCP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.
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DescriptionCP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetIL Receptor
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RecptorIL-1β
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Research Area——
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Indication——
Chemical Information
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CAS Number210825-31-3
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Formula Weight452.99
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Molecular FormulaC22H29ClN2O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (275.94 mM)
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SMILESO=S(C1=CC=CC(C(C)(O)C)=C1)(NC(NC2=C(C(C)C)C=C(Cl)C=C2C(C)C)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Perregaux D G , Mcniff P , Laliberte R , et al. Identification and characterization of a novel class of interleukin-1 post-translational processing inhibitors.[J]. Journal of Pharmacology & Experimental Therapeutics, 2001, 299(1):187.
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