Bengenin

Research use only, not for human use.

Bergenin, a polyphenol, is a potent antinarcotic agent with antioxidant action.

Bergenin, a polyphenol, is a potent antinarcotic agent with antioxidant action. (In Vitro):Bergenin (7.5-30μM; 24 hours) decreases the viability of HeLa cervical cancer cells (IC50=15 μM).Bergenin (7.5-30 μM; 24 hours) induces apoptosis in HeLa cervical cancer cells.(In Vivo):Pretreatment with Bergenin (12.5-100 mg/kg; i.p.; once) produces a dose-related inhibition of acetic acid-induced writhing in mice.

Bergenin (7.5-30μM; 24 hours) decreases the viability of HeLa cervical cancer cells (IC50=15 μM).Bergenin (7.5-30 μM; 24 hours) induces apoptosis in HeLa cervical cancer cells. Cell Viability Assay Cell Line:HeLa cervical cancer cells Concentration:7.5, 15, 30 μM Incubation Time:24 hours Result:Decreased the viability of HeLa cervical cancer cells.Cell Viability Assay Cell Line:HeLa cervical cancer cells Concentration:7.5, 15, 30 μM Incubation Time:24 hours Result:Induced apoptosis in HeLa cervical cancer cells.

Pretreatment with Bergenin (12.5-100 mg/kg; i.p.; once) produces a dose-related inhibition of acetic acid-induced writhing in mice. Animal Model:Male Swiss Webster C57BL/6 mice Dosage:12.5, 25, 50, 100 mg/kg Administration:i.p.; Once Result:Produced a dose-related inhibition of acetic acid-induced writhing in mice.

(–)-Bergenin | Cuscutin | NSC 661749

Apoptosis

IL Receptor

IL-1β| IL-6| NF-κB| NOD| TNF-α

Other Indications

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477-90-7

328.27

C14H16O9

>98% (HPLC)

DMSO: 66 mg/mL (201.05 mM)

COC1=C(C=C2C(=C1O)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)OC2=O)O

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(-20℃)

With Ice Pack

≥ 2 years