Levofloxacin hydrochloride
CAS No. 177325-13-2
Levofloxacin hydrochloride( —— )
Catalog No. M22740 CAS No. 177325-13-2
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 33 | In Stock |
|
Biological Information
-
Product NameLevofloxacin hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionLevofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA.
-
DescriptionLevofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA gyrase
-
RecptorDNA gyrase| Topo II| Topo IV
-
Research AreaRespiratory system
-
IndicationMycoplasma Pneumoniae Pneumonia
Chemical Information
-
CAS Number177325-13-2
-
Formula Weight397.8
-
Molecular FormulaC18H21ClFN3O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCl.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Schmitz FJ, et al. J Antimicrob ChemOthers. 1998 Apr;41(4):481-4.
molnova catalog
related products
-
Levofloxacin hydroch...
Levofloxacin hydrate is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
-
Ciprofloxacin hydroc...
A broad-spectrum antimicrobial carboxyfluoroquinoline.
-
Trovafloxacin
Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive. In HepG2 cells, Trovafloxacin (20 μM; 24 hours; ) and tumor necrosis factor (TNF; 4 ng/mL) incubation induces apoptosis and increases leakage of lactate dehydrogenase (LDH).
Cart
sales@molnova.com