Levofloxacin hydrochloride

CAS No. 177325-13-2

Levofloxacin hydrochloride( —— )

Catalog No. M22740 CAS No. 177325-13-2

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1G 33 In Stock

Biological Information

  • Product Name
    Levofloxacin hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA.
  • Description
    Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA gyrase
  • Recptor
    DNA gyrase| Topo II| Topo IV
  • Research Area
    Respiratory system
  • Indication
    Mycoplasma Pneumoniae Pneumonia

Chemical Information

  • CAS Number
    177325-13-2
  • Formula Weight
    397.8
  • Molecular Formula
    C18H21ClFN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schmitz FJ, et al. J Antimicrob ChemOthers. 1998 Apr;41(4):481-4.
molnova catalog
related products
  • Levofloxacin hydroch...

    Levofloxacin hydrate is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

  • Ciprofloxacin hydroc...

    A broad-spectrum antimicrobial carboxyfluoroquinoline.

  • Trovafloxacin

    Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive. In HepG2 cells, Trovafloxacin (20 μM; 24 hours; ) and tumor necrosis factor (TNF; 4 ng/mL) incubation induces apoptosis and increases leakage of lactate dehydrogenase (LDH).