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Levofloxacin hydrochloride (b)
CAS No. 138199-71-0
Levofloxacin hydrochloride (b)( RWJ 25213 | RWJ-25213 | RWJ25213 | Levofloxacin Hydrate | Levofloxacin Hemihydrate )
Catalog No. M11584 CAS No. 138199-71-0
Levofloxacin hydrate is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 36 | In Stock |
|
| 100MG | 43 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLevofloxacin hydrochloride (b)
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NoteResearch use only, not for human use.
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Brief DescriptionLevofloxacin hydrate is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
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DescriptionLevofloxacin hydrate is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
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In Vitro——
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In VivoAnimal Model:Matured male Albino miceDosage:10.7 mg/kg Administration:Intraperitoneal injection; 10.7 mg/kg, once daily for 10 days or 3 weeks Result:Induced severe congestion of blood vessels in the portal area, central veins with inflammatory cells infiltration, necrosis with pyknosis of cardiac muscle nuclei and apoptosis, degeneration and necrosis of hepatocytes.
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SynonymsRWJ 25213 | RWJ-25213 | RWJ25213 | Levofloxacin Hydrate | Levofloxacin Hemihydrate
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PathwayCell Cycle/DNA Damage
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TargetDNA gyrase
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RecptorDNA gyrase| Topo II| Topo IV
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number138199-71-0
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Formula Weight370.38
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Molecular FormulaC18H20FN3O4·1/2H2O
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Purity>98% (HPLC)
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SolubilityMEthanol: 10 mM
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SMILESO=C(C1=CN2C3=C(C=C(F)C(N4CCN(C)CC4)=C3OC[C@@H]2C)C1=O)O.[H]O[H].O=C(C5=CN6C7=C(C=C(F)C(N8CCN(C)CC8)=C7OC[C@@H]6C)C5=O)O
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Chemical Name(S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hemihydrate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Schmitz FJ, et al. J Antimicrob ChemOthers. 1998 Apr;41(4):481-4.
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