Cart
sales@molnova.com
Gemifioxacin mesylate
CAS No. 210353-53-0
Gemifioxacin mesylate( LB 20304a | SB 265805S )
Catalog No. M13343 CAS No. 210353-53-0
Gemifloxacin mesylate is an oral broad-spectrum quinolone antibacterial agent, used in the treatment of acute bacterial exacerbation of chronic bronchitis, and mild-to-moderate pneumonia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 27 | In Stock |
|
| 10MG | 42 | In Stock |
|
| 25MG | 70 | In Stock |
|
| 50MG | 105 | In Stock |
|
| 100MG | 150 | In Stock |
|
| 200MG | 223 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGemifioxacin mesylate
-
NoteResearch use only, not for human use.
-
Brief DescriptionGemifloxacin mesylate is an oral broad-spectrum quinolone antibacterial agent, used in the treatment of acute bacterial exacerbation of chronic bronchitis, and mild-to-moderate pneumonia.
-
DescriptionGemifloxacin mesylate is an oral broad-spectrum quinolone antibacterial agent, used in the treatment of acute bacterial exacerbation of chronic bronchitis, and mild-to-moderate pneumonia.(In Vitro):Gemifloxacin has higher antibacterial activity than Moxifloxacin (HY-66011A) against Streptococcus pneumoniae with a MIC90 of 0.06 μg/mL.Gemifloxacin has highly potent antibacterial activity against Penicillin-resistant strains of S. pneumoniae with a MIC90 of 0.03 μg/mL.(In Vivo):Gemifloxacin has favorable pharmacokinetic profile in animals after oral administration.
-
In VitroGemifloxacin has higher antibacterial activity than Moxifloxacin (HY-66011A) against Streptococcus pneumoniae with a MIC90 of 0.06 μg/mL.Gemifloxacin has highly potent antibacterial activity against Penicillin-resistant strains of S. pneumoniae with a MIC90 of 0.03 μg/mL.
-
In VivoGemifloxacin has favorable pharmacokinetic profile in animals after oral administration.Pharmacokinetic Parameters of Gemifloxacin in Sprague-Dawley rats and dogs.
-
SynonymsLB 20304a | SB 265805S
-
PathwayCell Cycle/DNA Damage
-
TargetDNA gyrase
-
RecptorDNA gyrase| Topo II
-
Research AreaInfection
-
Indication——
Chemical Information
-
CAS Number210353-53-0
-
Formula Weight485.49
-
Molecular FormulaC19H24FN5O7S
-
Purity>98% (HPLC)
-
SolubilityDMSO: 30mg/mL
-
SMILESCO/N=C/1\CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F.CS(=O)(=O)O
-
Chemical Name7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Ruiz J, et al. Int J Antimicrob Agents. 2003 Jul;22(1):73-6.
molnova catalog
related products
-
Norfloxacin
Norfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.
-
Ciprofloxacin hydroc...
A broad-spectrum antimicrobial carboxyfluoroquinoline.
-
Trovafloxacin
Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive. In HepG2 cells, Trovafloxacin (20 μM; 24 hours; ) and tumor necrosis factor (TNF; 4 ng/mL) incubation induces apoptosis and increases leakage of lactate dehydrogenase (LDH).
