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Norfloxacin
CAS No. 70458-96-7
Norfloxacin( Norfloxacin, AM-715, MK-366, Noroxin, Chibroxin )
Catalog No. M15708 CAS No. 70458-96-7
Norfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 37 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameNorfloxacin
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NoteResearch use only, not for human use.
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Brief DescriptionNorfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.
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DescriptionNorfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial DNA, thereby inhibiting cell division. This mechanism can also affect mammalian cell replication.(In Vitro):Norfloxacin (MK-0366) is a synthetic chemotherapeutic antibacterial agent occasionally used to treat common as well as complicated urinary tract infections. Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial DNA, thereby inhibiting cell division.There are currently three approved uses in the adult population (one of which is restricted) and the other ineffective due to bacterial resistance.
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In VitroNorfloxacin (MK-0366) is a synthetic chemotherapeutic antibacterial agent occasionally used to treat common as well as complicated urinary tract infections. Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial DNA, thereby inhibiting cell division.There are currently three approved uses in the adult population (one of which is restricted) and the other ineffective due to bacterial resistance.
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In Vivo——
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SynonymsNorfloxacin, AM-715, MK-366, Noroxin, Chibroxin
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PathwayCell Cycle/DNA Damage
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TargetDNA gyrase
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RecptorDNA gyrase| Topo II
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number70458-96-7
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Formula Weight319.34
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Molecular FormulaC16H18FN3O3
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Purity>98% (HPLC)
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SolubilityEthanol: <1 mg/mL (<1 mM); Water: <1 mg/mL (<1 mM); DMSO: <1 mg/mL (<1 mM)
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SMILESO=C(C1=CN(CC)C2=C(C=C(F)C(N3CCNCC3)=C2)C1=O)O
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Chemical Name1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Preissner S, et al. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43.
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