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4'-Methoxychalcone
CAS No. 959-23-9
4'-Methoxychalcone( —— )
Catalog No. M20874 CAS No. 959-23-9
4'-Methoxychalcone with a variety of pharmacological activities such as anti-tumor and anti-inflammatory activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | 27 | In Stock |
|
Biological Information
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Product Name4'-Methoxychalcone
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NoteResearch use only, not for human use.
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Brief Description4'-Methoxychalcone with a variety of pharmacological activities such as anti-tumor and anti-inflammatory activities.
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Description4'-Methoxychalcone with a variety of pharmacological activities such as anti-tumor and anti-inflammatory activities.
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In Vitro4'-Methoxychalcone (5 μM; 8 days) markedly increasesthe mRNA expression of adipogenic genes during adipocyte differentiation, PPARγ, aP2,FAS,adiponectin and GluT 4.4'-Methoxychalcone (5 μM; 8 days) reduces the upregulated mRNA expression of IL-6, PAI-1, and MCP-1 by TNF-α in preadipocyte 3T3-L1 cells.4'-Methoxychalcone (5 μM; 0-8 days) causes an increase in PPARγ expression during differentiation, while C/EBPβ protein expression is relatively unaffected. RT-PCR Cell Line:Preadipocyte 3T3-L1 cells Concentration:5 μM Incubation Time:0 day; 2 days; 4 days; 6 days; 8 days Result:Increased the mRNA expression of all adipogenic genes, except GluT1 in adipocyte.Western Blot Analysis Cell Line:Preadipocyte 3T3-L1 cells Concentration:5 μM Incubation Time:8 days Result:Increased PPARγ expression in adipocyte.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPPAR
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RecptorPPARγ
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Research Area——
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Indication——
Chemical Information
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CAS Number959-23-9
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Formula Weight238.28
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Molecular FormulaC16H14O2
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Purity>98% (HPLC)
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SolubilityDMSO:48mg/mL(201.44mM)
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SMILESCOc1ccc(C(=O)C=Cc2ccccc2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Younho Han Sung et al. Regulatory effects of 4-methoxychalcone on adipocyte differentiation through PPARγ activation and reverse effect on TNF-α in 3T3-L1 cells[J]. Food and Chemical Toxicology 2017.
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