CNQX
CAS No. 115066-14-3
CNQX( FG9065 )
Catalog No. M20706 CAS No. 115066-14-3
CNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 37 | In Stock |
|
| 10MG | 51 | In Stock |
|
| 25MG | 112 | In Stock |
|
| 50MG | 177 | In Stock |
|
| 100MG | 284 | In Stock |
|
| 200MG | 428 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCNQX
-
NoteResearch use only, not for human use.
-
Brief DescriptionCNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).
-
DescriptionCNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).
-
In Vitro——
-
In VivoAnimal Model:Male Wistar rats weighing 180-200 g Dosage:0.75, 1.5, and 3 mg/kg Administration:IP; 20 min before testing Result:Decreased the number of cocaine (IV; 0.25 mg/infusion) responses in a dose-dependent manner during the first 15-min cocaine-free interval.
-
SynonymsFG9065
-
PathwayNeuroscience
-
TargetGluR
-
RecptorAMPA
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number115066-14-3
-
Formula Weight232.15
-
Molecular FormulaC9H4N4O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:30 mg/mL (129.23 mM)
-
SMILES[O-][N+](=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1C#N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Blake J F Brown M W Collingridge G L . CNQX blocks acidic amino acid induced depolarizations and synaptic components mediated by non-NMDA receptors in rat hippocampal slices[J]. Neuroscience letters 1988 89(2):182-186.
molnova catalog
related products
-
Motolimod
Motolimod (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.
-
cis-PDA
cis-PDA is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.
-
S-(4-Hydroxybenzyl)g...
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
Cart
sales@molnova.com