CNQX

CAS No. 115066-14-3

CNQX( FG9065 )

Catalog No. M20706 CAS No. 115066-14-3

CNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 43 In Stock
5MG 39 In Stock
10MG 54 In Stock
25MG 118 In Stock
50MG 183 In Stock
100MG 294 In Stock
200MG 443 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CNQX
  • Note
    Research use only, not for human use.
  • Brief Description
    CNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).
  • Description
    CNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Wistar rats weighing 180-200 g Dosage:0.75, 1.5, and 3 mg/kg Administration:IP; 20 min before testing Result:Decreased the number of cocaine (IV; 0.25 mg/infusion) responses in a dose-dependent manner during the first 15-min cocaine-free interval.
  • Synonyms
    FG9065
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    AMPA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    115066-14-3
  • Formula Weight
    232.15
  • Molecular Formula
    C9H4N4O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:30 mg/mL (129.23 mM)
  • SMILES
    [O-][N+](=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1C#N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Blake J F Brown M W Collingridge G L . CNQX blocks acidic amino acid induced depolarizations and synaptic components mediated by non-NMDA receptors in rat hippocampal slices[J]. Neuroscience letters 1988 89(2):182-186.
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