CU-CPT-9a

CAS No. 2165340-32-7

CU-CPT-9a( —— )

Catalog No. M20662 CAS No. 2165340-32-7

CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM) that suppresses TLR8-mediated proinflammatory signaling in various cell lines.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 85 In Stock
2MG 46 In Stock
5MG 76 In Stock
10MG 122 In Stock
25MG 237 In Stock
50MG 423 In Stock
100MG 625 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CU-CPT-9a
  • Note
    Research use only, not for human use.
  • Brief Description
    CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM) that suppresses TLR8-mediated proinflammatory signaling in various cell lines.
  • Description
    CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM) that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    TLR
  • Recptor
    TLR8
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2165340-32-7
  • Formula Weight
    265.31
  • Molecular Formula
    C17H15NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:150 mg/mL (565.38 mM)
  • SMILES
    COc1ccc2c(ccnc2c1)-c1ccc(O)c(C)c1
  • Chemical Name
    2-Methyl-4-(7-methoxy-4-quinolinyl)phenol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang S Hu Z Tanji H et al. Small-molecule inhibition of TLR8 through stabilization of its resting state[J]. Nature Chemical Biology 2017 14(1):58-64.
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