CPG-52364( CPG 52364 | CPG52364 )

Catalog No. M10358 CAS No. 1093135-60-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

CPG-52364
Note

Research use only, not for human use.
Brief Description

CPG-52364 (CPG52364) is an orally available, small molecule TLR7/8/9 antagonist for the treatment of systemic lupus erythematosus and other autoimmune disorders.
Description

CPG-52364 (CPG52364) is an orally available, small molecule TLR7/8/9 antagonist for the treatment of systemic lupus erythematosus and other autoimmune disorders.Other Indication Phase 1 Discontinued.
In Vitro

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In Vivo

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Synonyms

CPG 52364 | CPG52364
Pathway

Immunology/Inflammation
Target

TLR
Recptor

TLR
Research Area

Other Indications
Indication

Other Disease

CAS Number

1093135-60-4
Formula Weight

492.624
Molecular Formula

C27H36N6O3
Purity

>98% (HPLC)
Solubility

——
SMILES

CN1CCN(C2=CC=C(C3=NC(NCCN4CCOCC4)=C5C=C(OC)C(OC)=CC5=N3)C=C2)CC1
Chemical Name

6,7-dimethoxy-2-(4-(4-methylpiperazin-1-yl)phenyl)-N-(2-morpholinoethyl)quinazolin-4-amine

1. Watanabe M, et al. ACS Med Chem Lett. 2014 Oct 2;5(11):1235-9. 2. Parkinson T. Curr Opin Mol Ther. 2008 Feb;10(1):21-31.

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