CAY10594

CAS No. 1130067-34-3

CAY10594( —— )

Catalog No. M20630 CAS No. 1130067-34-3

CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 147 In Stock
10MG 250 In Stock
25MG 447 In Stock
50MG 651 In Stock
100MG 888 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CAY10594
  • Note
    Research use only, not for human use.
  • Brief Description
    CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.
  • Description
    CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phospholipase
  • Recptor
    PLD2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1130067-34-3
  • Formula Weight
    428.5
  • Molecular Formula
    C26H28N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:20mg/ml(46.7mM)
  • SMILES
    O=C(NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc2ccccc2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lee SK Bae GH Kim YSet al.A phospholipase D2 inhibitor CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis[J].Sci Rep. 2019 May 10;9(1):7242.
molnova catalog
related products
  • Tanshinone I

    Tanshinone I is a pigment isolated from the herbal medicine Salvia miltiorrhiza Bunge.

  • GW 4869

    A cell-permeable, symmetrical dihydroimidazolo-amide compound that acts as a potent, specific, non-competitive inhibitor of N-SMase (neutral sphingomyelinase) [IC50?= ~ 1 μM, rat brain; Km?for sphingomyelin ~13 μM].

  • VU533

    VU533 (Nape-Pld activator) is a NAPE-PLD activator with an EC50 value of 0.30 μM.VU533 enhances NAPE-PLD activity and increases macrophage cytosolic burial.VU533 may be used in diseases associated with cardiometabolism.