Sephin1( NSC 65390 | IFB-088 )

Catalog No. M23468 CAS No. 13098-73-2

Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	28	In Stock
10MG	33	In Stock
25MG	57	In Stock
50MG	83	In Stock
100MG	126	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Sephin1
Note

Research use only, not for human use.
Brief Description

Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α
Description

Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α.
In Vitro

——
In Vivo

——
Synonyms

NSC 65390 | IFB-088
Pathway

Metabolic Enzyme/Protease
Target

Phospholipase
Recptor

phosphatase PPP1R15A
Research Area

——
Indication

——

Chemical Information

CAS Number

13098-73-2
Formula Weight

196.64
Molecular Formula

C8H9ClN4
Purity

>98% (HPLC)
Solubility

DMSO:7mg/ml(35.60mM);H2O:insoluble
SMILES

NC(N)=NN=Cc(cccc1)c1Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ruiz A , Zuazo J , Ortiz-Sanz C , et al. Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response[J]. International Journal of Molecular Sciences, 2020, 21(17):6088.

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