Sephin1( NSC 65390 | IFB-088 )

Catalog No. M23468 CAS No. 13098-73-2

Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
25MG	59	In Stock
50MG	90	In Stock
100MG	136	In Stock
200MG	203	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Sephin1
Note

Research use only, not for human use.
Brief Description

Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α
Description

Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α.
In Vitro

——
In Vivo

——
Synonyms

NSC 65390 | IFB-088
Pathway

Metabolic Enzyme/Protease
Target

Phospholipase
Recptor

phosphatase PPP1R15A
Research Area

——
Indication

——

Chemical Information

CAS Number

13098-73-2
Formula Weight

196.64
Molecular Formula

C8H9ClN4
Purity

>98% (HPLC)
Solubility

DMSO:7mg/ml(35.60mM);H2O:insoluble
SMILES

NC(N)=NN=Cc(cccc1)c1Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ruiz A , Zuazo J , Ortiz-Sanz C , et al. Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response[J]. International Journal of Molecular Sciences, 2020, 21(17):6088.

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