Cosmosiin
CAS No. 578-74-5
Cosmosiin( Apigetrin )
Catalog No. M18842 CAS No. 578-74-5
Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
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| 5MG | 38 | In Stock |
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| 10MG | 61 | In Stock |
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| 25MG | 123 | In Stock |
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| 50MG | 198 | In Stock |
|
| 100MG | 323 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 765 | In Stock |
|
| 1G | 1014 | In Stock |
|
Biological Information
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Product NameCosmosiin
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NoteResearch use only, not for human use.
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Brief DescriptionCosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation.
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DescriptionApigetrin is a flavanoid derivved from dandelions which may inhibit neuroinflammation in BV-2 microglia and have a neuroprotective effect in HT22 hippocampal cells. This molecule may also hinder cancer progression by inhibiting various pathways such as STAT3/JAK2.
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In VitroApigenin 7-glucoside exhibits significant anti-proliferative activity against B16F10 melanoma cells after 24 and 48 h of incubation. Apigenin-7-glucosideprovoks an increase of subG0/G1, S and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases. Apigenin-7-glucosideenhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells.Apigenin 7-glucoside specifically induces the differentiation of CD34+ cells towards the erythroid lineage and inhibited the myeloid differentiation. Apigenin 7-glucoside has strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner.
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In Vivo——
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SynonymsApigetrin
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PathwayOthers
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TargetAntioxidant
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RecptorHIV
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number578-74-5
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Formula Weight432.38
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Molecular FormulaC21H20O10
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 30 mg/mL; 69.38 mM
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SMILESC1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O
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Chemical Name7-(beta-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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