Clodronate Disodium

CAS No. 22560-50-5

Clodronate Disodium( —— )

Catalog No. M18264 CAS No. 22560-50-5

Clodronate Disodium, a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG 33 In Stock
200MG Get Quote In Stock
500MG 88 In Stock
1G 130 In Stock

Biological Information

  • Product Name
    Clodronate Disodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Clodronate Disodium, a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.
  • Description
    Clodronate Disodium, a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Lewis rats, aged 7 weeksDosage:6.25, 12.5, and 25 mg/kg Administration:P.o.; daily for 28 days Result:Hindpaw swelling was significantly smaller than in adjuvant-arthritis (AA)-control at 25 mg/kg on days 21 and 28 (87 and 88% of AA-control, respectively) and at 12.5 mg/kg on day 28.
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PDK
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    22560-50-5
  • Formula Weight
    288.86
  • Molecular Formula
    CH4Cl2O6P0·2Na
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (346.19 mM)
  • SMILES
    [Na+].[Na+].OP([O-])(=O)C(Cl)(Cl)P(O)([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Frith JC, et al. J Bone Miner Res, 1997, 12(9), 1358-1367.
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