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GSK2334470
CAS No. 1227911-45-6
GSK2334470( GSK2334470 | GSK 2334470 | GSK-2334470 )
Catalog No. M10881 CAS No. 1227911-45-6
GSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM in a cell-free assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 83 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 75 | In Stock |
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| 25MG | 141 | In Stock |
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| 50MG | 252 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK2334470
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NoteResearch use only, not for human use.
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Brief DescriptionGSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM in a cell-free assay.
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DescriptionGSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM in a cell-free assay, with no activity at other close related AGC-kinases.
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In Vitro——
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In Vivo——
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SynonymsGSK2334470 | GSK 2334470 | GSK-2334470
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PathwayPI3K/Akt/mTOR signaling
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TargetPDK
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RecptorPDK1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1227911-45-6
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Formula Weight462.59
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Molecular FormulaC25H34N8O
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Purity>98% (HPLC)
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SolubilityEthanol: 90 mg/mL (194.55 mM); DMSO: 90 mg/mL (194.55 mM)
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SMILESO=C([C@@H]1CN(C2=NC(NC)=NC(C3=CC4=C(C=C3)C(N)=NN4)=C2)[C@H](C)CC1)NC5CCCCC5
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Chemical Name(3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-N-cyclohexyl-6-methylpiperidine-3-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Najafov A, et al. Biochem J, 2011, 433(2), 357-369.
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