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KPLH1130

CAS No. 906669-07-6

KPLH1130( —— )

Catalog No. M24944 CAS No. 906669-07-6

KPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 188 In Stock
5MG 217 In Stock
10MG 351 In Stock
25MG 591 In Stock
50MG 823 In Stock
100MG 1107 In Stock
200MG Get Quote In Stock
500MG 2260 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    KPLH1130
  • Note
    Research use only, not for human use.
  • Brief Description
    KPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.
  • Description
    KPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PDK
  • Recptor
    PDK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    906669-07-6
  • Formula Weight
    283.28
  • Molecular Formula
    C15H13N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:130 mg/mL (458.91 mM; Need ultrasonic)
  • SMILES
    O=C1NN=C(C2=CC=C(O)C=C2O)N1C3=CC=C(C)C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Min BK, et al. Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype. Front Immunol. 2019 May 7;10:944.
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