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KPLH1130
CAS No. 906669-07-6
KPLH1130( —— )
Catalog No. M24944 CAS No. 906669-07-6
KPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 188 | In Stock |
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| 5MG | 217 | In Stock |
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| 10MG | 351 | In Stock |
|
| 25MG | 591 | In Stock |
|
| 50MG | 823 | In Stock |
|
| 100MG | 1107 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2260 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKPLH1130
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NoteResearch use only, not for human use.
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Brief DescriptionKPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.
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DescriptionKPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetPDK
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RecptorPDK
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Research Area——
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Indication——
Chemical Information
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CAS Number906669-07-6
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Formula Weight283.28
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Molecular FormulaC15H13N3O3
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Purity>98% (HPLC)
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SolubilityDMSO:130 mg/mL (458.91 mM; Need ultrasonic)
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SMILESO=C1NN=C(C2=CC=C(O)C=C2O)N1C3=CC=C(C)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Min BK, et al. Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype. Front Immunol. 2019 May 7;10:944.
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