Ochromycinone

CAS No. 111540-00-2

Ochromycinone( STA21 | Ochromycinone | NSC 628869 )

Catalog No. M17821 CAS No. 111540-00-2

STA-21 is a selective STAT3 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 145 In Stock
5MG 132 In Stock
10MG 227 In Stock
25MG 468 In Stock
50MG 807 In Stock
100MG 1088 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Ochromycinone
  • Note
    Research use only, not for human use.
  • Brief Description
    STA-21 is a selective STAT3 inhibitor.
  • Description
    STA-21 is a promising STAT-3 inhibitor that reciprocally regulates Th17 and Treg cells, inhibits osteoclastogenesis in mice and humans and alleviates autoimmune inflammation in an experimental model of rheumatoid arthritis. STA-21 improved the clinical course of arthritis in IL-1Ra-KO mice. It increased not only the number of Treg cells but also the function of the Treg cells. It also suppressed Th17 cells and osteoclast formation. These data suggest that STA-21 might be an effective treatment for patients with RA.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    STA21 | Ochromycinone | NSC 628869
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    STAT3
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    111540-00-2
  • Formula Weight
    306.31
  • Molecular Formula
    C19H14O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 16.67 mg/mL (54.42 mM)
  • SMILES
    CC1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O
  • Chemical Name
    8-hydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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