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Home - Products - Metabolic Enzyme/Protease - Casein Kinase - SGI-7079

SGI-7079

CAS No. 1239875-86-5

SGI-7079( SGI-7079 | SGI 7079 | SGI7079 )

Catalog No. M17214 CAS No. 1239875-86-5

SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 59 In Stock
2MG 33 In Stock
5MG 53 In Stock
10MG 93 In Stock
25MG 188 In Stock
50MG 237 In Stock
100MG 346 In Stock
200MG Get Quote In Stock
500MG 808 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    SGI-7079
  • Note
    Research use only, not for human use.
  • Brief Description
    SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors.
  • Description
    SGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 effectively inhibited Axl activation in the presence of exogenous Gas6 ligand. SGI-7079 inhibited tumor growth in a dose dependent manner. Axl is a potential therapeutic target for overcoming EGFR inhibitor resistance.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SGI-7079 | SGI 7079 | SGI7079
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Casein Kinase
  • Recptor
    Met| RET| FLT3| Yes| AXL| Mer
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1239875-86-5
  • Formula Weight
    455.53
  • Molecular Formula
    C26H26FN7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 34 mg/mL. 74.64 mM
  • SMILES
    CN1CCN(CC1)c1ccc(Nc2nc3c(c(C)c[nH]3)c(n2)c2cc(CC#N)ccc2)cc1F
  • Chemical Name
    2-(3-(2-((3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Myers SH, et al. J Med Chem. 2016, 59(8):3593-608.
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