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Home - Products - Metabolic Enzyme/Protease - Casein Kinase - TTP 22

TTP 22

CAS No. 329907-28-0

TTP 22( TTP 22 | TTP-22 | TTP22 )

Catalog No. M14092 CAS No. 329907-28-0

TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TTP 22
  • Note
    Research use only, not for human use.
  • Brief Description
    TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM.
  • Description
    TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM; shows selectivity for CK2 over JNK3, ROCK1, and MET(IC50> 10 uM).
  • In Vitro
    TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM.
  • In Vivo
    ——
  • Synonyms
    TTP 22 | TTP-22 | TTP22
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Casein Kinase
  • Recptor
    CK2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    329907-28-0
  • Formula Weight
    330.42
  • Molecular Formula
    C16H14N2O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL
  • SMILES
    O=C(O)CCSC1=C(C(C2=CC=C(C)C=C2)=CS3)C3=NC=N1
  • Chemical Name
    3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]-propanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Golub AG, et al. Eur J Med Chem. 2011 Mar;46(3): 870-6.
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