Cart
sales@molnova.com
Obicetrapib
CAS No. 866399-87-3
Obicetrapib( AMG-899 | AMG899 | TA-8995 | DEX-001 )
Catalog No. M16296 CAS No. 866399-87-3
Obicetrapib (AMG-899, TA-8995, DEX-001) is a potent, ora cholesteryl ester transfer protein (CETP) inhibitor for treatment of dyslipidaemia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 212 | In Stock |
|
| 5MG | 154 | In Stock |
|
| 10MG | 216 | In Stock |
|
| 25MG | 390 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameObicetrapib
-
NoteResearch use only, not for human use.
-
Brief DescriptionObicetrapib (AMG-899, TA-8995, DEX-001) is a potent, ora cholesteryl ester transfer protein (CETP) inhibitor for treatment of dyslipidaemia.
-
DescriptionObicetrapib (AMG-899, TA-8995, DEX-001) is a potent, ora cholesteryl ester transfer protein (CETP) inhibitor for treatment of dyslipidaemia.Dyslipidemia Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsAMG-899 | AMG899 | TA-8995 | DEX-001
-
PathwayMetabolic Enzyme/Protease
-
TargetCETP
-
RecptorCETP
-
Research AreaCardiovascular Disease
-
IndicationDyslipidemia
Chemical Information
-
CAS Number866399-87-3
-
Formula Weight722.609
-
Molecular FormulaC32H31F9N4O5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCC1CC(C2=C(N1C(=O)OCC)C=CC(=C2)C(F)(F)F)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C4=NC=C(C=N4)OCCCC(=O)O
-
Chemical Name4-[2-[[3,5-bis(trifluoromethyl)phenyl]methyl-[(2R,4S)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinolin-4-yl]amino]pyrimidin-5-yl]oxybutanoic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ford J, et al. Br J Clin Pharmacol. 2014 Sep;78(3):498-508.
2. Hovingh GK, et al. Lancet. 2015 Aug 1;386(9992):452-60.
molnova catalog
related products
-
BMS-795311
BMS-795311 is a potent and orally available CETP inhibitor with IC50 of 3.8 nM, inhibits cholesteryl ester (CE) transfer with IC50 of 0.22 uM.
-
TAP-311
TAP-311 is a novel potent and selective CETP inhibitor with plasma IC50 of 62 nM.
-
CKD-519
CKD-519 (Rocacetrapib, CKD519) is a potent, selective cholesteryl ester transfer protein (CETP) inhibitor, inhibits the CETP-mediated transfer of cholesteryl ester in human serum with IC50 of 2.3 nM.
