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NB 001
CAS No. 686301-48-4
NB 001( NB001 | NB-001 )
Catalog No. M15621 CAS No. 686301-48-4
A potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 200 | Get Quote |
|
| 10MG | 295 | Get Quote |
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| 25MG | 498 | Get Quote |
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| 50MG | 710 | Get Quote |
|
| 100MG | 963 | Get Quote |
|
| 500MG | 1935 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameNB 001
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition).
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DescriptionA potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition); displays >10-fold selectivity over AC5/6/7/8; shows analgesic effect in animal models of neuropathic pain, without no significant effect on behavioral anxiety.
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In Vitro——
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In Vivo——
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SynonymsNB001 | NB-001
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PathwayMetabolic Enzyme/Protease
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TargetAdenylate Cyclase
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RecptorAdenylate Cyclase
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Research Area——
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Indication——
Chemical Information
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CAS Number686301-48-4
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Formula Weight264.333
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Molecular FormulaC12H20N6O
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Purity>98% (HPLC)
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Solubility——
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SMILESOCCCCCNCCN1C=NC2=C(N)N=CN=C12
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Chemical Name5-[[2-(6-amino-9H-purin-9-yl)ethyl]amino]-1-pentanol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wang H, et al. Sci Transl Med. 2011 Jan 12;3(65):65ra3.
2. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.
3. Zhang MM, et al. Mol Brain. 2014 Jun 16;7:47.
4. Sethna F, et al. Nat Commun. 2017 Feb 20;8:14359.
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