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JW55

CAS No. 664993-53-7

JW55( Tankyrase 1/2 Inhibitor IV )

Catalog No. M15535 CAS No. 664993-53-7

JW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). JW55 decreased auto-PARsylation of TNKS1/2 in vitro with IC50 values of 1.9 uM and 830 nM respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 33 In Stock
25MG 69 In Stock
50MG 111 In Stock
100MG 183 In Stock
200MG 272 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    JW55
  • Note
    Research use only, not for human use.
  • Brief Description
    JW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). JW55 decreased auto-PARsylation of TNKS1/2 in vitro with IC50 values of 1.9 uM and 830 nM respectively.
  • Description
    JW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). JW55 decreased auto-PARsylation of TNKS1/2 in vitro with IC50 values of 1.9 uM and 830 nM respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Tankyrase 1/2 Inhibitor IV
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    PPAR
  • Recptor
    TNKS1| TNKS2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    664993-53-7
  • Formula Weight
    434.48
  • Molecular Formula
    C25H26N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO, Ethanol: 100 mM
  • SMILES
    O=C(C1=CC=CO1)NC2=CC=C(C(NCC3(C4=CC=C(OC)C=C4)CCOCC3)=O)C=C2
  • Chemical Name
    N-(4-(((4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)carbamoyl)phenyl)furan-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Waaler J, et al. Y Res. 2012 Jun 1;72(11):2822-32.
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