Methocarbamol( AHR 85 | Guaiacol Glyceryl Ether Carbamate | Guaiphenesin Carbamate | NSC 170960 )

Catalog No. M14894 CAS No. 532-03-6

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Methocarbamol
Note

Research use only, not for human use.
Brief Description

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.
Description

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.(In Vitro):Methocarbamol (2 mM; for 20 min) significantly increases the decay times of the EPCs and those of the EPPs induced by the phrenic nerve stimulation.Methocarbamol has no effect on Nav1.7 currents. (In Vivo):Methocarbamol (200 mg/kg; ip) has Muscle relaxant activity of 88.96%.
In Vitro

Methocarbamol (2?mM; for 20?min) significantly increases the decay times of the EPCs and those of the EPPs induced by the phrenic nerve stimulation.Methocarbamol has no effect on Nav1.7 currents.
In Vivo

Methocarbamol (200?mg/kg; ip) has Muscle relaxant activity of 88.96%. Animal Model:Mice with weight 20-30?g Dosage:200?mg/kg Administration:IP; single dose Result:Had Muscle relaxant activity of 88.96%.
Synonyms

AHR 85 | Guaiacol Glyceryl Ether Carbamate | Guaiphenesin Carbamate | NSC 170960
Pathway

Membrane Transporter/Ion Channel
Target

Carbonic Anhydrase
Recptor

CA1
Research Area

Metabolic Disease
Indication

——

CAS Number

532-03-6
Formula Weight

241.24
Molecular Formula

C11H15NO5
Purity

>98% (HPLC)
Solubility

Ethanol: 48 mg/mL (198.97 mM); Water: 2 mg/mL (8.29 mM); DMSO: 48 mg/mL (198.97 mM)
SMILES

COC1=CC=CC=C1OCC(COC(=O)N)O
Chemical Name

[2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate

1.Parr JS, Khalifah RG. J Biol Chem. 1992 Dec 15; 267(35):25044-50.

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