Cart
sales@molnova.com
Disulfamide
CAS No. 671-88-5
Disulfamide( —— )
Catalog No. M35441 CAS No. 671-88-5
Disulfamide is an orally active carbonic anhydrase inhibitor with an IC50 value of 0.07 μM. Disulfamide has a diuretic effect by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal convoluted tubules.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 104 | In Stock |
|
| 10MG | 159 | In Stock |
|
| 25MG | 310 | In Stock |
|
| 50MG | 414 | In Stock |
|
| 100MG | 559 | In Stock |
|
| 200MG | 755 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDisulfamide
-
NoteResearch use only, not for human use.
-
Brief DescriptionDisulfamide is an orally active carbonic anhydrase inhibitor with an IC50 value of 0.07 μM. Disulfamide has a diuretic effect by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal convoluted tubules.
-
DescriptionDisulfamide, an orally active diuretic, is a carbonic anhydrase inhibitor with the IC50 value of 0.07 μM. Disulfamide leads to diuresis by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal tubule.
-
In Vitro——
-
In VivoDisulfamide (intraperitoneal injection, 200 mg/kg, once) has potential blood glucose raising properties in male Wistar rats.Animal Model:Male Wistar rats weighing between 200-300 g Dosage:200 mg/kg Administration: Intraperitoneal injection; once Result:Resulted in elevated blood sugar levels from an initial blood glucose concentration of 143.1 mg/100 mL to a one hour later final concentration of 194.6 mg/100 mL, an increase of 36%.
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetCarbonic Anhydrase
-
RecptorCarbonic Anhydrase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number671-88-5
-
Formula Weight284.74
-
Molecular FormulaC7H9ClN2O4S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESS(N)(=O)(=O)C1=CC(S(N)(=O)=O)=C(Cl)C=C1C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. CT Supuran, et al. Carbonic anhydrase inhibitors: Synthesis and inhibitory properties of 1,3,4-thiadiazole-2,5-bissulfonamide. European Journal of Medicinal Chemistry,Volume 31, Issue 11, 1996, Pages 843-846.
molnova catalog
related products
-
Acetazolamide sodium
Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used for indications such as epilepsy, glaucoma, edema, and altitude sickness.
-
hCAII-IN-9
hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50 values of 1.18 μM for hCA II, 0.17 μM for hCA IX, and 2.99 μM for hCA XII. It is not blood-brain barrier permeable.
-
CAIX Inhibitor S4
CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM.
