Acetazolamide sodium( —— )

Catalog No. M35403 CAS No. 1424-27-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Acetazolamide sodium
Note

Research use only, not for human use.
Brief Description

Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used for indications such as epilepsy, glaucoma, edema, and altitude sickness.
Description

Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. Acetazolamide sodium has diuretic, antihypertensive and anti-gonococcal activities.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Carbonic Anhydrase
Recptor

Carbonic Anhydrase
Research Area

——
Indication

——

CAS Number

1424-27-7
Formula Weight

244.23
Molecular Formula

C4H5N4NaO3S2
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : ≥ 100 mg/mL (407.76 mM)DMSO : 100 mg/mL (407.76 mM; Ultrasonic )
SMILES

O=C(C)NC1=NN=C(S(=O)([NH-])=O)S1.[Na+]
Chemical Name

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1. Bayat Mokhtari R, et al.Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. BMC Cancer. 2017 Feb 24;17(1):156.?

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