Dimethylfraxetin( 678-Trimethoxycoumarin | Fraxetin dimethyl ether )

Catalog No. M20278 CAS No. 6035-49-0

Dimethylfraxetin is a Carbonic anhydrase inhibitor（Ki：0.0097 μM）

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	89	In Stock
5MG	72	In Stock
10MG	129	In Stock
25MG	259	In Stock
50MG	365	In Stock
100MG	514	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
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Biological Information

Product Name

Dimethylfraxetin
Note

Research use only, not for human use.
Brief Description

Dimethylfraxetin is a Carbonic anhydrase inhibitor（Ki：0.0097 μM）
Description

Dimethylfraxetin is a Carbonic anhydrase inhibitor.（Ki：0.0097 μM）.
In Vitro

At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study.
In Vivo

——
Synonyms

678-Trimethoxycoumarin | Fraxetin dimethyl ether
Pathway

Membrane Transporter/Ion Channel
Target

Carbonic Anhydrase
Recptor

Carbonic Anhydrase
Research Area

——
Indication

——

Chemical Information

CAS Number

6035-49-0
Formula Weight

236.22
Molecular Formula

C12H12O5
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL?(529.17 mM)
SMILES

COc1cc2ccc(=O)oc2c(OC)c1OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Davis R A Vullo D Maresca A et al. Natural product coumarins that inhibit human carbonic anhydrases[J]. Bioorganic & medicinal chemistry 2012 21(6):1539-1543.

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