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NSC112200

CAS No. 28293-38-1

NSC112200( NSC 112200 )

Catalog No. M13860 CAS No. 28293-38-1

NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    NSC112200
  • Note
    Research use only, not for human use.
  • Brief Description
    NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2.
  • Description
    NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2, promotes proteasomal degradation of EZH2 and inhibits the viability of TNBC cells; NSC112200 is a mixture of 2,5-dibromo-3,6-dimethyl-1,4- benzenediol and 2,5-dibromo-3,6-dimethyl-1,4-benzoquinone.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC 112200
  • Pathway
    Proteasome/Ubiquitin
  • Target
    DUB
  • Recptor
    DUB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    28293-38-1
  • Formula Weight
    293.942
  • Molecular Formula
    C8H6Br2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=C(C(=O)C(=C(C1=O)Br)C)Br
  • Chemical Name
    2,5-Dibromo-3,6-dimethyl-2,5-cyclohexadiene-1,4-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang P, et al. Cell Rep. 2018 Apr 17;23(3):823-837.
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