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NSC112200
CAS No. 28293-38-1
NSC112200( NSC 112200 )
Catalog No. M13860 CAS No. 28293-38-1
NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameNSC112200
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NoteResearch use only, not for human use.
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Brief DescriptionNSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2.
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DescriptionNSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2, promotes proteasomal degradation of EZH2 and inhibits the viability of TNBC cells; NSC112200 is a mixture of 2,5-dibromo-3,6-dimethyl-1,4- benzenediol and 2,5-dibromo-3,6-dimethyl-1,4-benzoquinone.
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In Vitro——
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In Vivo——
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SynonymsNSC 112200
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorDUB
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Research Area——
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Indication——
Chemical Information
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CAS Number28293-38-1
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Formula Weight293.942
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Molecular FormulaC8H6Br2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=C(C(=O)C(=C(C1=O)Br)C)Br
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Chemical Name2,5-Dibromo-3,6-dimethyl-2,5-cyclohexadiene-1,4-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang P, et al. Cell Rep. 2018 Apr 17;23(3):823-837.
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